3gen
From Proteopedia
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===The 1.6 A crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound=== | ===The 1.6 A crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3gen]] is a 1 chain structure of [[Tyrosine kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GEN OCA]. | |
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| + | ==See Also== | ||
| + | *[[Tyrosine kinase|Tyrosine kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020052711</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
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[[Category: Silvian, L F.]] | [[Category: Silvian, L F.]] | ||
[[Category: Wildes, C P.]] | [[Category: Wildes, C P.]] | ||
| - | [[Category: Acetylation]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Bruton's tyrosine kinase]] | [[Category: Bruton's tyrosine kinase]] | ||
[[Category: Complex]] | [[Category: Complex]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
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[[Category: Nucleus]] | [[Category: Nucleus]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Sh2 domain]] | [[Category: Sh2 domain]] | ||
[[Category: Sh3 domain]] | [[Category: Sh3 domain]] | ||
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[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
| - | [[Category: Zinc]] | ||
[[Category: Zinc-finger]] | [[Category: Zinc-finger]] | ||
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Revision as of 20:41, 25 July 2012
Contents |
The 1.6 A crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound
Template:ABSTRACT PUBMED 20052711
About this Structure
3gen is a 1 chain structure of Tyrosine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Marcotte DJ, Liu YT, Arduini RM, Hession CA, Miatkowski K, Wildes CP, Cullen PF, Hong V, Hopkins BT, Mertsching E, Jenkins TJ, Romanowski MJ, Baker DP, Silvian LF. Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for tec family kinases. Protein Sci. 2010 Jan 5. PMID:20052711 doi:10.1002/pro.321
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Arduini, R M. | Baker, D P. | Cullen, P F. | Hession, C A. | Hopkins, B. | Jenkins, T J. | Liu, Y T. | Marcotte, D J. | Mertsching, E. | Miatkowski, K. | Romanowski, M J. | Silvian, L F. | Wildes, C P. | Atp-binding | Bruton's tyrosine kinase | Complex | Disease mutation | Kinase | Membrane | Metal-binding | Nucleotide-binding | Nucleus | Phosphoprotein | Sh2 domain | Sh3 domain | Tec-family | Transferase | Tyrosine-protein kinase | Zinc-finger
