3gen

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Template:STRUCTURE 3gen

Contents

The 1.6 A crystal structure of human bruton's tyrosine kinase bound to a pyrrolopyrimidine-containing compound

Template:ABSTRACT PUBMED 20052711

About this Structure

3gen is a 1 chain structure of Tyrosine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Marcotte DJ, Liu YT, Arduini RM, Hession CA, Miatkowski K, Wildes CP, Cullen PF, Hong V, Hopkins BT, Mertsching E, Jenkins TJ, Romanowski MJ, Baker DP, Silvian LF. Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for tec family kinases. Protein Sci. 2010 Jan 5. PMID:20052711 doi:10.1002/pro.321

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