1buz
From Proteopedia
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==Overview== | ==Overview== | ||
| - | The establishment of differential gene expression in sporulating Bacillus | + | The establishment of differential gene expression in sporulating Bacillus subtilis involves four protein components, one of which, SpoIIAA, undergoes phosphorylation and dephosphorylation. We have used NMR spectroscopy to determine the solution structure of the nonphosphorylated form of SpoIIAA. The structure shows a fold consisting of a four-stranded beta-sheet and four alpha-helices. Knowledge of the structure helps to account for the phenotype of several strains of B. subtilis that carry known spoIIAA mutations and should facilitate investigations of the conformational consequences of phosphorylation. |
==About this Structure== | ==About this Structure== | ||
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[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Campbell, I | + | [[Category: Campbell, I D.]] |
[[Category: Comfort, D.]] | [[Category: Comfort, D.]] | ||
[[Category: Kovacs, H.]] | [[Category: Kovacs, H.]] | ||
[[Category: Lord, M.]] | [[Category: Lord, M.]] | ||
| - | [[Category: Yudkin, M | + | [[Category: Yudkin, M D.]] |
[[Category: anti-anti sigma factor]] | [[Category: anti-anti sigma factor]] | ||
[[Category: kinase substrate]] | [[Category: kinase substrate]] | ||
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[[Category: transcription regulator]] | [[Category: transcription regulator]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 11:59:21 2008'' |
Revision as of 09:59, 21 February 2008
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SOLUTION STRUCTURE OF SPOIIAA, A PHOSPHORYLATABLE COMPONENT OF THE SYSTEM THAT REGULATES TRANSCRIPTION FACTOR SIGMA-F OF BACILLUS SUBTILIS NMR, MINIMIZED AVERAGE STRUCTURE
Overview
The establishment of differential gene expression in sporulating Bacillus subtilis involves four protein components, one of which, SpoIIAA, undergoes phosphorylation and dephosphorylation. We have used NMR spectroscopy to determine the solution structure of the nonphosphorylated form of SpoIIAA. The structure shows a fold consisting of a four-stranded beta-sheet and four alpha-helices. Knowledge of the structure helps to account for the phenotype of several strains of B. subtilis that carry known spoIIAA mutations and should facilitate investigations of the conformational consequences of phosphorylation.
About this Structure
1BUZ is a Single protein structure of sequence from Bacillus subtilis. Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
Solution structure of SpoIIAA, a phosphorylatable component of the system that regulates transcription factor sigmaF of Bacillus subtilis., Kovacs H, Comfort D, Lord M, Campbell ID, Yudkin MD, Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5067-71. PMID:9560229
Page seeded by OCA on Thu Feb 21 11:59:21 2008
