4ajp
From Proteopedia
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[[Image:4ajp.png|left|200px]] | [[Image:4ajp.png|left|200px]] | ||
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{{STRUCTURE_4ajp| PDB=4ajp | SCENE= }} | {{STRUCTURE_4ajp| PDB=4ajp | SCENE= }} | ||
===Human LDHA in complex with 2-((4-(4-((3-((2-methyl-1,3-benzothiazol- 6yl)amino)-3-oxo-propyl)amino)-4-oxo-butyl)phenyl)methyl)propanedioic acid=== | ===Human LDHA in complex with 2-((4-(4-((3-((2-methyl-1,3-benzothiazol- 6yl)amino)-3-oxo-propyl)amino)-4-oxo-butyl)phenyl)methyl)propanedioic acid=== | ||
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{{ABSTRACT_PUBMED_22417091}} | {{ABSTRACT_PUBMED_22417091}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[4ajp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJP OCA]. | + | [[4ajp]] is a 4 chain structure of [[Lactate Dehydrogenase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AJP OCA]. |
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| + | ==See Also== | ||
| + | *[[Lactate Dehydrogenase|Lactate Dehydrogenase]] | ||
==Reference== | ==Reference== | ||
Revision as of 20:58, 25 July 2012
Contents |
Human LDHA in complex with 2-((4-(4-((3-((2-methyl-1,3-benzothiazol- 6yl)amino)-3-oxo-propyl)amino)-4-oxo-butyl)phenyl)methyl)propanedioic acid
Template:ABSTRACT PUBMED 22417091
About this Structure
4ajp is a 4 chain structure of Lactate Dehydrogenase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Ward RA, Brassington C, Breeze AL, Caputo A, Critchlow S, Davies G, Goodwin L, Hassall G, Greenwood R, Holdgate GA, Mrosek M, Norman RA, Pearson S, Tart J, Tucker JA, Vogtherr M, Whittaker D, Wingfield J, Winter J, Hudson K. Design and synthesis of novel lactate dehydrogenase a inhibitors by fragment-based lead generation. J Med Chem. 2012 Apr 12;55(7):3285-306. Epub 2012 Mar 26. PMID:22417091 doi:10.1021/jm201734r
