2j38
From Proteopedia
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{{STRUCTURE_2j38| PDB=2j38 | SCENE= }} | {{STRUCTURE_2j38| PDB=2j38 | SCENE= }} | ||
===CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX=== | ===CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX=== | ||
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{{ABSTRACT_PUBMED_16982192}} | {{ABSTRACT_PUBMED_16982192}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2j38]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J38 OCA]. | + | [[2j38]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J38 OCA]. |
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| + | ==See Also== | ||
| + | *[[Factor Xa|Factor Xa]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016982192</ref><ref group="xtra">PMID:017338508</ref><references group="xtra"/> |
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Watson, N S.]] | [[Category: Watson, N S.]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
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[[Category: Complex]] | [[Category: Complex]] | ||
[[Category: Egf-like domain]] | [[Category: Egf-like domain]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
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[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
Revision as of 21:00, 25 July 2012
Contents |
CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX
Template:ABSTRACT PUBMED 16982192
About this Structure
2j38 is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Senger S, Convery MA, Chan C, Watson NS. Arylsulfonamides: a study of the relationship between activity and conformational preferences for a series of factor Xa inhibitors. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5731-5. Epub 2006 Sep 18. PMID:16982192 doi:http://dx.doi.org/10.1016/j.bmcl.2006.08.092
- Chan C, Borthwick AD, Brown D, Burns-Kurtis CL, Campbell M, Chaudry L, Chung CW, Convery MA, Hamblin JN, Johnstone L, Kelly HA, Kleanthous S, Patikis A, Patel C, Pateman AJ, Senger S, Shah GP, Toomey JR, Watson NS, Weston HE, Whitworth C, Young RJ, Zhou P. Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl }sulfonamides. J Med Chem. 2007 Apr 5;50(7):1546-57. Epub 2007 Mar 6. PMID:17338508 doi:http://dx.doi.org/10.1021/jm060870c
