2vkm
From Proteopedia
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===CRYSTAL STRUCTURE OF GRL-8234 BOUND TO BACE (BETA-SECRETASE)=== | ===CRYSTAL STRUCTURE OF GRL-8234 BOUND TO BACE (BETA-SECRETASE)=== | ||
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{{ABSTRACT_PUBMED_18180160}} | {{ABSTRACT_PUBMED_18180160}} | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[2vkm]] is a 4 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKM OCA]. | |
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+ | ==See Also== | ||
+ | *[[Beta secretase|Beta secretase]] | ||
==Reference== | ==Reference== | ||
- | + | <ref group="xtra">PMID:018180160</ref><references group="xtra"/> | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Ghosh, A K.]] | [[Category: Ghosh, A K.]] | ||
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[[Category: Tang, J.]] | [[Category: Tang, J.]] | ||
[[Category: A-beta]] | [[Category: A-beta]] | ||
- | [[Category: Alternative splicing]] | ||
[[Category: Alzheimer]] | [[Category: Alzheimer]] | ||
[[Category: App]] | [[Category: App]] | ||
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[[Category: X- ray]] | [[Category: X- ray]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 17 13:20:52 2008'' |
Revision as of 21:15, 25 July 2012
Contents |
CRYSTAL STRUCTURE OF GRL-8234 BOUND TO BACE (BETA-SECRETASE)
Template:ABSTRACT PUBMED 18180160
About this Structure
2vkm is a 4 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Ghosh AK, Kumaragurubaran N, Hong L, Kulkarni S, Xu X, Miller HB, Reddy DS, Weerasena V, Turner R, Chang W, Koelsch G, Tang J. Potent memapsin 2 (beta-secretase) inhibitors: design, synthesis, protein-ligand X-ray structure, and in vivo evaluation. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1031-6. Epub 2008 Jan 3. PMID:18180160 doi:S0960-894X(07)01473-4
Categories: Homo sapiens | Ghosh, A K. | Hong, L. | Tang, J. | A-beta | Alzheimer | App | Aspartic protease | Aspartyl protease | Bace | Beta secretase | Drug design | Glycoprotein | Hydrolase | Memapsin | Membrane | Protease | Transmembrane | X- ray | Zymogen