2vkm

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Revision as of 21:15, 25 July 2012

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Template:STRUCTURE 2vkm

Contents 1 CRYSTAL STRUCTURE OF GRL-8234 BOUND TO BACE (BETA-SECRETASE) 2 About this Structure 3 See Also 4 Reference

CRYSTAL STRUCTURE OF GRL-8234 BOUND TO BACE (BETA-SECRETASE)

Template:ABSTRACT PUBMED 18180160

About this Structure

2vkm is a 4 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Ghosh AK, Kumaragurubaran N, Hong L, Kulkarni S, Xu X, Miller HB, Reddy DS, Weerasena V, Turner R, Chang W, Koelsch G, Tang J. Potent memapsin 2 (beta-secretase) inhibitors: design, synthesis, protein-ligand X-ray structure, and in vivo evaluation. Bioorg Med Chem Lett. 2008 Feb 1;18(3):1031-6. Epub 2008 Jan 3. PMID:18180160 doi:S0960-894X(07)01473-4