2ibt
From Proteopedia
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===Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position and an abasic site analog at the target base partner position=== | ===Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position and an abasic site analog at the target base partner position=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | [[2ibt]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IBT OCA]. | + | [[2ibt]] is a 6 chain structure of [[DNA methyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IBT OCA]. |
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| + | ==See Also== | ||
| + | *[[DNA methyltransferase|DNA methyltransferase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017455934</ref><ref group="xtra">PMID:011175890</ref><ref group="xtra">PMID:008995524</ref><references group="xtra"/> |
[[Category: Thermus aquaticus]] | [[Category: Thermus aquaticus]] | ||
[[Category: Lenz, T.]] | [[Category: Lenz, T.]] | ||
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[[Category: Dna methyltransferase]] | [[Category: Dna methyltransferase]] | ||
[[Category: Nucleotide flipping]] | [[Category: Nucleotide flipping]] | ||
| - | [[Category: Transferase | + | [[Category: Transferase-dna complex]] |
Revision as of 21:21, 25 July 2012
Contents |
Crystal structure of the adenine-specific DNA methyltransferase M.TaqI complexed with the cofactor analog AETA and a 10 bp DNA containing 2-aminopurine at the target position and an abasic site analog at the target base partner position
Template:ABSTRACT PUBMED 17455934
About this Structure
2ibt is a 6 chain structure of DNA methyltransferase with sequence from Thermus aquaticus. Full crystallographic information is available from OCA.
See Also
Reference
- Lenz T, Bonnist EY, Pljevaljcic G, Neely RK, Dryden DT, Scheidig AJ, Jones AC, Weinhold E. 2-Aminopurine flipped into the active site of the adenine-specific DNA methyltransferase M.TaqI: crystal structures and time-resolved fluorescence. J Am Chem Soc. 2007 May 16;129(19):6240-8. Epub 2007 Apr 25. PMID:17455934 doi:http://dx.doi.org/10.1021/ja069366n
- Blumenthal RM, Cheng X. A Taq attack displaces bases. Nat Struct Biol. 2001 Feb;8(2):101-3. PMID:11175890 doi:http://dx.doi.org/10.1038/84072
- Schluckebier G, Kozak M, Bleimling N, Weinhold E, Saenger W. Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI. J Mol Biol. 1997 Jan 10;265(1):56-67. PMID:8995524 doi:http://dx.doi.org/10.1006/jmbi.1996.0711
