3p0y
From Proteopedia
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[[Image:3p0y.png|left|200px]] | [[Image:3p0y.png|left|200px]] | ||
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{{STRUCTURE_3p0y| PDB=3p0y | SCENE= }} | {{STRUCTURE_3p0y| PDB=3p0y | SCENE= }} | ||
===anti-EGFR/HER3 Fab DL11 in complex with domain III of EGFR extracellular region=== | ===anti-EGFR/HER3 Fab DL11 in complex with domain III of EGFR extracellular region=== | ||
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==See Also== | ==See Also== | ||
- | *[[Epidermal Growth Factor Receptor]] | + | *[[Epidermal Growth Factor Receptor|Epidermal Growth Factor Receptor]] |
==Reference== | ==Reference== |
Revision as of 21:24, 25 July 2012
Contents |
anti-EGFR/HER3 Fab DL11 in complex with domain III of EGFR extracellular region
Template:ABSTRACT PUBMED 22014573
About this Structure
3p0y is a 3 chain structure of Epidermal Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Schaefer G, Haber L, Crocker LM, Shia S, Shao L, Dowbenko D, Totpal K, Wong A, Lee CV, Stawicki S, Clark R, Fields C, Lewis Phillips GD, Prell RA, Danilenko DM, Franke Y, Stephan JP, Hwang J, Wu Y, Bostrom J, Sliwkowski MX, Fuh G, Eigenbrot C. A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies. Cancer Cell. 2011 Oct 18;20(4):472-86. PMID:22014573 doi:10.1016/j.ccr.2011.09.003