3b8r
From Proteopedia
(Difference between revisions)
m (Protected "3b8r" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
[[Image:3b8r.png|left|200px]] | [[Image:3b8r.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3b8r", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3b8r| PDB=3b8r | SCENE= }} | {{STRUCTURE_3b8r| PDB=3b8r | SCENE= }} | ||
===Crystal structure of the VEGFR2 kinase domain in complex with a naphthamide inhibitor=== | ===Crystal structure of the VEGFR2 kinase domain in complex with a naphthamide inhibitor=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_18324759}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 18324759 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_18324759}} | {{ABSTRACT_PUBMED_18324759}} | ||
Revision as of 21:41, 25 July 2012
Contents |
Crystal structure of the VEGFR2 kinase domain in complex with a naphthamide inhibitor
Template:ABSTRACT PUBMED 18324759
About this Structure
3b8r is a 2 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Weiss MM, Harmange JC, Polverino AJ, Bauer D, Berry L, Berry V, Borg G, Bready J, Chen D, Choquette D, Coxon A, Demelfi T, Doerr N, Estrada J, Flynn J, Graceffa RF, Harriman SP, Kaufman S, La DS, Long A, Neervannan S, Patel VF, Potashman M, Regal K, Roveto PM, Schrag ML, Starnes C, Tasker A, Teffera Y, Whittington DA, Zanon R. Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors. J Med Chem. 2008 Mar 27;51(6):1668-80. Epub 2008 Mar 7. PMID:18324759 doi:10.1021/jm701098w
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Gu, Y. | Long, A M. | Whittington, D A. | Zhao, H. | Angiogenesis | Atp-binding | Developmental protein | Differentiation | Glycoprotein | Host-virus interaction | Immunoglobulin domain | Membrane | Nucleotide-binding | Phosphorylation | Receptor tyrosine kinase | Transferase | Transmembrane | Tyrosine-protein kinase
