1yy9
From Proteopedia
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[[Image:1yy9.png|left|200px]] | [[Image:1yy9.png|left|200px]] | ||
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{{STRUCTURE_1yy9| PDB=1yy9 | SCENE= }} | {{STRUCTURE_1yy9| PDB=1yy9 | SCENE= }} | ||
===Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225=== | ===Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225=== | ||
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{{ABSTRACT_PUBMED_15837620}} | {{ABSTRACT_PUBMED_15837620}} | ||
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==See Also== | ==See Also== | ||
| - | *[[Epidermal Growth Factor Receptor]] | + | *[[Epidermal Growth Factor Receptor|Epidermal Growth Factor Receptor]] |
| - | *[[Monoclonal Antibody]] | + | *[[Monoclonal Antibody|Monoclonal Antibody]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015837620</ref><references group="xtra"/> |
[[Category: Epidermal Growth Factor Receptor]] | [[Category: Epidermal Growth Factor Receptor]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Revision as of 21:51, 25 July 2012
Contents |
Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225
Template:ABSTRACT PUBMED 15837620
About this Structure
1yy9 is a 3 chain structure of Epidermal Growth Factor Receptor and Monoclonal Antibody with sequence from Homo sapiens and Mus musculus, homo sapiens. The June 2010 RCSB PDB Molecule of the Month feature on Epidermal Growth Factor Receptor by David Goodsell is 10.2210/rcsb_pdb/mom_2010_6. Full crystallographic information is available from OCA.
See Also
Reference
- Li S, Schmitz KR, Jeffrey PD, Wiltzius JJ, Kussie P, Ferguson KM. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell. 2005 Apr;7(4):301-11. PMID:15837620 doi:10.1016/j.ccr.2005.03.003
Categories: Epidermal Growth Factor Receptor | Homo sapiens | Mus musculus, homo sapiens | RCSB PDB Molecule of the Month | Receptor protein-tyrosine kinase | Ferguson, K M. | Jeffrey, P D. | Kussie, P. | Li, S. | Schmitz, K R. | Wiltzius, J J.W. | Antigen:antibody complex | Antitumor | Cell surface receptor | Drug | Fab fragment | Glycoprotein | Immune system-transferase complex | Tyrosine kinase
