1n15
From Proteopedia
(New page: 200px<br /> <applet load="1n15" size="450" color="white" frame="true" align="right" spinBox="true" caption="1n15, resolution 2.90Å" /> '''FOLLOWING THE C HEM...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1N15 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]] with HEC and DHE as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.2 1.9.3.2]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1N15 OCA]]. | + | 1N15 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]] with HEC and DHE as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Transferred_entry:_1.7.2.1 Transferred entry: 1.7.2.1]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.9.3.2 1.9.3.2]]. Structure known Active Sites: NIA and NIB. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1N15 OCA]]. |
==Reference== | ==Reference== | ||
| Line 14: | Line 14: | ||
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| + | [[Category: Transferred entry: 1.7.2.1]] | ||
[[Category: Cambillau, C.]] | [[Category: Cambillau, C.]] | ||
[[Category: Nurizzo, D.]] | [[Category: Nurizzo, D.]] | ||
| Line 27: | Line 28: | ||
[[Category: pseudomonas aeruginosa]] | [[Category: pseudomonas aeruginosa]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:42:53 2007'' |
Revision as of 11:38, 30 October 2007
|
FOLLOWING THE C HEME REDUCTION IN NITRITE REDUCTASE FROM PSEUDOMONAS AERUGINOSA
Overview
The structures of nitrite reductase from Paracoccus denitrificans GB17, (NiR-Pd) and Pseudomonas aeruginosa (NiR-Pa) have been described for the, oxidized and reduced state (Fulop, V., Moir, J. W. B., Ferguson, S. J., and Hajdu, J. (1995) Cell 81, 369-377; Nurizzo, D., Silvestrini, M. C., Mathieu, M., Cutruzzola, F., Bourgeois, D., Fulop, V., Hajdu, J., Brunori, M., Tegoni, M., and Cambillau, C. (1997) Structure 5, 1157-1171; Nurizzo, D., Cutruzzola, F., Arese, M., Bourgeois, D., Brunori, M., Cambillau, C. , and Tegoni, M. (1998) Biochemistry 37, 13987-13996). Major conformational, rearrangements are observed in the extreme states although they are more, substantial in NiR-Pd. The four structures differ significantly in the c, heme domains. Upon reduction, a His17/Met106 heme-ligand ... [(full description)]
About this Structure
1N15 is a [Single protein] structure of sequence from [Pseudomonas aeruginosa] with HEC and DHE as [ligands]. Active as [Transferred entry: 1.7.2.1], with EC number [1.9.3.2]. Structure known Active Sites: NIA and NIB. Full crystallographic information is available from [OCA].
Reference
Does the reduction of c heme trigger the conformational change of crystalline nitrite reductase?, Nurizzo D, Cutruzzola F, Arese M, Bourgeois D, Brunori M, Cambillau C, Tegoni M, J Biol Chem. 1999 May 21;274(21):14997-5004. PMID:10329702
Page seeded by OCA on Tue Oct 30 13:42:53 2007
