3fl5

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[[Image:3fl5.png|left|200px]]
[[Image:3fl5.png|left|200px]]
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{{STRUCTURE_3fl5| PDB=3fl5 | SCENE= }}
{{STRUCTURE_3fl5| PDB=3fl5 | SCENE= }}
===Protein kinase CK2 in complex with the inhibitor Quinalizarin===
===Protein kinase CK2 in complex with the inhibitor Quinalizarin===
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{{ABSTRACT_PUBMED_19432557}}
{{ABSTRACT_PUBMED_19432557}}
==About this Structure==
==About this Structure==
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[[3fl5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FL5 OCA].
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[[3fl5]] is a 1 chain structure of [[Casein kinase]] with sequence from [http://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FL5 OCA].
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==See Also==
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*[[Casein kinase|Casein kinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:19432557</ref><ref group="xtra">PMID:18242640</ref><ref group="xtra">PMID:10882732</ref><references group="xtra"/>
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<ref group="xtra">PMID:019432557</ref><ref group="xtra">PMID:018242640</ref><ref group="xtra">PMID:010882732</ref><references group="xtra"/>
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Zea mays]]
[[Category: Zea mays]]

Revision as of 22:08, 25 July 2012

Image:3fl5.png

Template:STRUCTURE 3fl5

Contents

Protein kinase CK2 in complex with the inhibitor Quinalizarin

Template:ABSTRACT PUBMED 19432557

About this Structure

3fl5 is a 1 chain structure of Casein kinase with sequence from Zea mays. Full crystallographic information is available from OCA.

See Also

Reference

  • Cozza G, Mazzorana M, Papinutto E, Bain J, Elliott M, di Maira G, Gianoncelli A, Pagano MA, Sarno S, Ruzzene M, Battistutta R, Meggio F, Moro S, Zagotto G, Pinna LA. Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2. Biochem J. 2009 Jul 15;421(3):387-95. PMID:19432557 doi:10.1042/BJ20090069
  • Raaf J, Klopffleisch K, Issinger OG, Niefind K. The catalytic subunit of human protein kinase CK2 structurally deviates from its maize homologue in complex with the nucleotide competitive inhibitor emodin. J Mol Biol. 2008 Mar 14;377(1):1-8. Epub 2008 Jan 11. PMID:18242640 doi:http://dx.doi.org/10.1016/j.jmb.2008.01.008
  • Battistutta R, Sarno S, De Moliner E, Papinutto E, Zanotti G, Pinna LA. The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2. J Biol Chem. 2000 Sep 22;275(38):29618-22. PMID:10882732 doi:10.1074/jbc.M004257200

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