3ixj

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[[Image:3ixj.png|left|200px]]
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{{STRUCTURE_3ixj| PDB=3ixj | SCENE= }}
{{STRUCTURE_3ixj| PDB=3ixj | SCENE= }}
===Crystal structure of beta-secretase 1 in complex with selective beta-secretase 1 inhibitor===
===Crystal structure of beta-secretase 1 in complex with selective beta-secretase 1 inhibitor===
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{{ABSTRACT_PUBMED_20128595}}
{{ABSTRACT_PUBMED_20128595}}
==About this Structure==
==About this Structure==
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3IXJ is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IXJ OCA].
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[[3ixj]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IXJ OCA].
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==See Also==
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*[[Beta secretase|Beta secretase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:20128595</ref><references group="xtra"/>
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<ref group="xtra">PMID:020128595</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Lindberg, J.]]
[[Category: Lindberg, J.]]
[[Category: Nystrom, S.]]
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[[Category: Alternative splicing]]
 
[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Bace]]
[[Category: Bace]]
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[[Category: Inhibitor]]
[[Category: Inhibitor]]
[[Category: Membrane]]
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[[Category: Polymorphism]]
 
[[Category: Protease]]
[[Category: Protease]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 3 15:55:17 2010''
 

Revision as of 22:31, 25 July 2012

Template:STRUCTURE 3ixj

Contents

Crystal structure of beta-secretase 1 in complex with selective beta-secretase 1 inhibitor

Template:ABSTRACT PUBMED 20128595

About this Structure

3ixj is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Bjorklund C, Oscarson S, Benkestock K, Borkakoti N, Jansson K, Lindberg J, Vrang L, Hallberg A, Rosenquist A, Samuelsson B. Design and synthesis of potent and selective BACE-1 inhibitors. J Med Chem. 2010 Feb 25;53(4):1458-64. PMID:20128595 doi:10.1021/jm901168f

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