2hwh
From Proteopedia
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===HCV NS5B allosteric inhibitor complex=== | ===HCV NS5B allosteric inhibitor complex=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2hwh]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HWH OCA]. | |
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| + | ==See Also== | ||
| + | *[[RNA polymerase|RNA polymerase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016934455</ref><references group="xtra"/> |
[[Category: Hepatitis c virus]] | [[Category: Hepatitis c virus]] | ||
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
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[[Category: Ns5b]] | [[Category: Ns5b]] | ||
[[Category: Rdrp]] | [[Category: Rdrp]] | ||
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[[Category: Viral rna-directed rna polymerase]] | [[Category: Viral rna-directed rna polymerase]] | ||
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Revision as of 22:55, 25 July 2012
Contents |
HCV NS5B allosteric inhibitor complex
Template:ABSTRACT PUBMED 16934455
About this Structure
2hwh is a 2 chain structure of RNA polymerase with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See Also
Reference
- Yan S, Appleby T, Larson G, Wu JZ, Hamatake R, Hong Z, Yao N. Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5888-91. Epub 2006 Aug 24. PMID:16934455 doi:10.1016/j.bmcl.2006.08.056
