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4dl4
From Proteopedia
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| - | [[Image:4dl4. | + | [[Image:4dl4.png|left|200px]] |
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{{STRUCTURE_4dl4| PDB=4dl4 | SCENE= }} | {{STRUCTURE_4dl4| PDB=4dl4 | SCENE= }} | ||
===Human DNA polymerase eta inserting dCMPNPP opposite the 3'G of cisplatin crosslinked Gs (Pt-GG1).=== | ===Human DNA polymerase eta inserting dCMPNPP opposite the 3'G of cisplatin crosslinked Gs (Pt-GG1).=== | ||
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{{ABSTRACT_PUBMED_22529383}} | {{ABSTRACT_PUBMED_22529383}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[4dl4]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DL4 OCA]. | + | [[4dl4]] is a 3 chain structure of [[DNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DL4 OCA]. |
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| + | ==See Also== | ||
| + | *[[DNA polymerase|DNA polymerase]] | ||
==Reference== | ==Reference== | ||
Revision as of 22:55, 25 July 2012
Contents |
Human DNA polymerase eta inserting dCMPNPP opposite the 3'G of cisplatin crosslinked Gs (Pt-GG1).
Template:ABSTRACT PUBMED 22529383
About this Structure
4dl4 is a 3 chain structure of DNA polymerase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Zhao Y, Biertumpfel C, Gregory MT, Hua YJ, Hanaoka F, Yang W. Structural basis of human DNA polymerase eta-mediated chemoresistance to cisplatin. Proc Natl Acad Sci U S A. 2012 Apr 23. PMID:22529383 doi:10.1073/pnas.1202681109
Categories: DNA-directed DNA polymerase | Homo sapiens | Biertumpfel, Christian | Gregory, Mark | Hanaoka, Fumio | Hua, Yue-Jin | Yang, Wei | Zhao, Ye | Chemoresistence | Cisplatin | Dna distorsion | Human dna polymerse eta | Inhibition | Kinetic | Molecular splint | Nucleotidyl transfer reaction | Pcna | Second tls polymerase | Transferase-dna-inhibitor complex | Translesion synthesis
