1pwu
From Proteopedia
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===Crystal Structure of Anthrax Lethal Factor complexed with (3-(N-hydroxycarboxamido)-2-isobutylpropanoyl-Trp-methylamide), a known small molecule inhibitor of matrix metalloproteases.=== | ===Crystal Structure of Anthrax Lethal Factor complexed with (3-(N-hydroxycarboxamido)-2-isobutylpropanoyl-Trp-methylamide), a known small molecule inhibitor of matrix metalloproteases.=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1pwu]] is a 2 chain structure of [[Anthrax Lethal Factor]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PWU OCA]. | |
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| + | ==See Also== | ||
| + | *[[Anthrax Lethal Factor|Anthrax Lethal Factor]] | ||
==Reference== | ==Reference== | ||
| - | + | <ref group="xtra">PMID:014718924</ref><references group="xtra"/> | |
[[Category: Bacillus anthracis]] | [[Category: Bacillus anthracis]] | ||
| - | [[Category: Single protein]] | ||
[[Category: Liddington, R C.]] | [[Category: Liddington, R C.]] | ||
[[Category: Schwarzenbacher, R.]] | [[Category: Schwarzenbacher, R.]] | ||
[[Category: Wong, T Y.]] | [[Category: Wong, T Y.]] | ||
[[Category: Anthrax toxin]] | [[Category: Anthrax toxin]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Hydroxamic acid.]] | [[Category: Hydroxamic acid.]] | ||
[[Category: Lethal factor]] | [[Category: Lethal factor]] | ||
[[Category: Small molecule peptidic inhibitor]] | [[Category: Small molecule peptidic inhibitor]] | ||
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Revision as of 22:57, 25 July 2012
Contents |
Crystal Structure of Anthrax Lethal Factor complexed with (3-(N-hydroxycarboxamido)-2-isobutylpropanoyl-Trp-methylamide), a known small molecule inhibitor of matrix metalloproteases.
Template:ABSTRACT PUBMED 14718924
About this Structure
1pwu is a 2 chain structure of Anthrax Lethal Factor with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.
See Also
Reference
- Turk BE, Wong TY, Schwarzenbacher R, Jarrell ET, Leppla SH, Collier RJ, Liddington RC, Cantley LC. The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor. Nat Struct Mol Biol. 2004 Jan;11(1):60-6. Epub 2003 Dec 29. PMID:14718924 doi:10.1038/nsmb708
