3h5u
From Proteopedia
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{{STRUCTURE_3h5u| PDB=3h5u | SCENE= }} | {{STRUCTURE_3h5u| PDB=3h5u | SCENE= }} | ||
===Hepatitis C virus polymerase NS5B with saccharin inhibitor 1=== | ===Hepatitis C virus polymerase NS5B with saccharin inhibitor 1=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3h5u]] is a 2 chain structure of [[RNA polymerase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H5U OCA]. | |
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| + | ==See Also== | ||
| + | *[[RNA polymerase|RNA polymerase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019709881</ref><references group="xtra"/> |
[[Category: Hepatitis c virus]] | [[Category: Hepatitis c virus]] | ||
[[Category: RNA-directed RNA polymerase]] | [[Category: RNA-directed RNA polymerase]] | ||
[[Category: Ghate, M.]] | [[Category: Ghate, M.]] | ||
[[Category: Harris, S F.]] | [[Category: Harris, S F.]] | ||
| - | [[Category: Acetylation]] | ||
[[Category: Apoptosis]] | [[Category: Apoptosis]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Capsid protein]] | [[Category: Capsid protein]] | ||
[[Category: Cell membrane]] | [[Category: Cell membrane]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] | ||
[[Category: Endoplasmic reticulum]] | [[Category: Endoplasmic reticulum]] | ||
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[[Category: Transferase rna-dependent rna polymerase]] | [[Category: Transferase rna-dependent rna polymerase]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
| - | [[Category: Ubl conjugation]] | ||
[[Category: Viral nucleoprotein]] | [[Category: Viral nucleoprotein]] | ||
[[Category: Virion]] | [[Category: Virion]] | ||
| - | [[Category: Zinc]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 08:41:21 2009'' | ||
Revision as of 23:10, 25 July 2012
Contents |
Hepatitis C virus polymerase NS5B with saccharin inhibitor 1
Template:ABSTRACT PUBMED 19709881
About this Structure
3h5u is a 2 chain structure of RNA polymerase with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.
See Also
Reference
- de Vicente J, Hendricks RT, Smith DB, Fell JB, Fischer J, Spencer SR, Stengel PJ, Mohr P, Robinson JE, Blake JF, Hilgenkamp RK, Yee C, Adjabeng G, Elworthy TR, Li J, Wang B, Bamberg JT, Harris SF, Wong A, Leveque VJ, Najera I, Le Pogam S, Rajyaguru S, Ao-Ieong G, Alexandrova L, Larrabee S, Brandl M, Briggs A, Sukhtankar S, Farrell R. Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5652-6. Epub 2009 Aug 8. PMID:19709881 doi:10.1016/j.bmcl.2009.08.022
Categories: Hepatitis c virus | RNA-directed RNA polymerase | Ghate, M. | Harris, S F. | Apoptosis | Atp-binding | Capsid protein | Cell membrane | Disulfide bond | Endoplasmic reticulum | Envelope protein | Fusion protein | Glycoprotein | Hcv | Helicase | Hepatitis | Host-virus interaction | Hydrolase | Interferon antiviral system evasion | Lipid droplet | Lipoprotein | Membrane | Metal-binding | Mitochondrion | Multifunctional enzyme | Ns5b | Nucleotide-binding | Nucleotidyltransferase | Nucleus | Oncogene | Palmitate | Phosphoprotein | Protease | Ribonucleoprotein | Rna replication | Rna-binding | Rna-directed rna polymerase | Secreted | Serine protease | Sh3-binding | Thiol protease | Transcription | Transcription regulation | Transferase | Transferase rna-dependent rna polymerase | Transmembrane | Viral nucleoprotein | Virion
