2c8y
From Proteopedia
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===THROMBIN INHIBITORS=== | ===THROMBIN INHIBITORS=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2c8y]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C8Y OCA]. | |
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| + | ==See Also== | ||
| + | *[[Hirudin|Hirudin]] | ||
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016480269</ref><references group="xtra"/> |
[[Category: Hirudo medicinalis]] | [[Category: Hirudo medicinalis]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Acute phase]] | [[Category: Acute phase]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
| - | [[Category: Calcium]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Gamma-carboxyglutamic acid]] | [[Category: Gamma-carboxyglutamic acid]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
| - | [[Category: Hydrolase]] | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
[[Category: Kringle]] | [[Category: Kringle]] | ||
[[Category: Plasma]] | [[Category: Plasma]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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Revision as of 23:13, 25 July 2012
Contents |
THROMBIN INHIBITORS
Template:ABSTRACT PUBMED 16480269
About this Structure
2c8y is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Howard N, Abell C, Blakemore W, Chessari G, Congreve M, Howard S, Jhoti H, Murray CW, Seavers LC, van Montfort RL. Application of fragment screening and fragment linking to the discovery of novel thrombin inhibitors. J Med Chem. 2006 Feb 23;49(4):1346-55. PMID:16480269 doi:10.1021/jm050850v
Categories: Hirudo medicinalis | Homo sapiens | Thrombin | Abell, C. | Blakemore, W. | Carr, R. | Chessari, G. | Congreve, M. | Howard, N. | Howard, S. | Jhoti, H. | Montfort, R L.M Van. | Murray, C W. | Seavers, L C.A. | Acute phase | Blood coagulation | Disease mutation | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase-hydrolase inhibitor complex | Kringle | Plasma | Protease | Serine protease | Zymogen
