2fdp

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{{Seed}}
 
[[Image:2fdp.png|left|200px]]
[[Image:2fdp.png|left|200px]]
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{{STRUCTURE_2fdp| PDB=2fdp | SCENE= }}
{{STRUCTURE_2fdp| PDB=2fdp | SCENE= }}
===Crystal structure of beta-secretase complexed with an amino-ethylene inhibitor===
===Crystal structure of beta-secretase complexed with an amino-ethylene inhibitor===
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{{ABSTRACT_PUBMED_16451048}}
{{ABSTRACT_PUBMED_16451048}}
==About this Structure==
==About this Structure==
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2FDP is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FDP OCA].
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[[2fdp]] is a 3 chain structure of [[Beta secretase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FDP OCA].
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==See Also==
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*[[Beta secretase|Beta secretase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:16451048</ref><references group="xtra"/>
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<ref group="xtra">PMID:016451048</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Memapsin 2]]
[[Category: Memapsin 2]]
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[[Category: Aspartyl protease]]
[[Category: Aspartyl protease]]
[[Category: Bace]]
[[Category: Bace]]
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[[Category: Hydrolase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:47:53 2009''
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Revision as of 23:28, 25 July 2012

Image:2fdp.png

Template:STRUCTURE 2fdp

Contents

Crystal structure of beta-secretase complexed with an amino-ethylene inhibitor

Template:ABSTRACT PUBMED 16451048

About this Structure

2fdp is a 3 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Yang W, Lu W, Lu Y, Zhong M, Sun J, Thomas AE, Wilkinson JM, Fucini RV, Lam M, Randal M, Shi XP, Jacobs JW, McDowell RS, Gordon EM, Ballinger MD. Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1. J Med Chem. 2006 Feb 9;49(3):839-42. PMID:16451048 doi:10.1021/jm0509142

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OCA

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