1a9u

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{{STRUCTURE_1a9u| PDB=1a9u | SCENE= }}
{{STRUCTURE_1a9u| PDB=1a9u | SCENE= }}
===THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB203580===
===THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB203580===
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{{ABSTRACT_PUBMED_9753691}}
{{ABSTRACT_PUBMED_9753691}}
==About this Structure==
==About this Structure==
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1A9U is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A9U OCA].
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[[1a9u]] is a 1 chain structure of [[Mitogen-activated protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A9U OCA].
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==See Also==
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*[[Mitogen-activated protein kinase|Mitogen-activated protein kinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:9753691</ref><references group="xtra"/>
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<ref group="xtra">PMID:009753691</ref><ref group="xtra">PMID:009624152</ref><ref group="xtra">PMID:017035239</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Abdel-Meguid, S.]]
[[Category: Abdel-Meguid, S.]]
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[[Category: Serine/threonine-protein kinase]]
[[Category: Serine/threonine-protein kinase]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:51:44 2009''
 

Revision as of 23:34, 25 July 2012

Image:1a9u.png


PDB ID 1a9u

Drag the structure with the mouse to rotate
1a9u, resolution 2.50Å ()
Ligands:
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Contents

THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB203580

Template:ABSTRACT PUBMED 9753691

About this Structure

1a9u is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Wang Z, Canagarajah BJ, Boehm JC, Kassisa S, Cobb MH, Young PR, Abdel-Meguid S, Adams JL, Goldsmith EJ. Structural basis of inhibitor selectivity in MAP kinases. Structure. 1998 Sep 15;6(9):1117-28. PMID:9753691
  • Gum RJ, McLaughlin MM, Kumar S, Wang Z, Bower MJ, Lee JC, Adams JL, Livi GP, Goldsmith EJ, Young PR. Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket. J Biol Chem. 1998 Jun 19;273(25):15605-10. PMID:9624152
  • Avvakumov GV, Walker JR, Xue S, Finerty PJ Jr, Mackenzie F, Newman EM, Dhe-Paganon S. Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8). J Biol Chem. 2006 Dec 8;281(49):38061-70. Epub 2006 Oct 11. PMID:17035239 doi:10.1074/jbc.M606704200

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