2b7d

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Revision as of 23:57, 25 July 2012

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Template:STRUCTURE 2b7d

Contents 1 Factor VIIa Inhibitors: Chemical Optimization, Preclinical Pharmacokinetics, Pharmacodynamics, and Efficacy in a Baboon Thrombosis Model 2 About this Structure 3 See Also 4 Reference

Factor VIIa Inhibitors: Chemical Optimization, Preclinical Pharmacokinetics, Pharmacodynamics, and Efficacy in a Baboon Thrombosis Model

Template:ABSTRACT PUBMED 16412633

About this Structure

2b7d is a 3 chain structure of Factor VIIa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Factor VIIa

Reference

• Young WB, Mordenti J, Torkelson S, Shrader WD, Kolesnikov A, Rai R, Liu L, Hu H, Leahy EM, Green MJ, Sprengeler PA, Katz BA, Yu C, Janc JW, Elrod KC, Marzec UM, Hanson SR. Factor VIIa inhibitors: chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in an arterial baboon thrombosis model. Bioorg Med Chem Lett. 2006 Apr 1;16(7):2037-41. Epub 2006 Jan 18. PMID:16412633 doi:10.1016/j.bmcl.2005.12.059