3fv8

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Revision as of 00:13, 26 July 2012

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Template:STRUCTURE 3fv8

Contents 1 JNK3 bound to piperazine amide inhibitor, SR2774. 2 About this Structure 3 See Also 4 Reference

JNK3 bound to piperazine amide inhibitor, SR2774.

Template:ABSTRACT PUBMED 19433357

About this Structure

3fv8 is a 1 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Mitogen-activated protein kinase

Reference

• Shin Y, Chen W, Habel J, Duckett D, Ling YY, Koenig M, He Y, Vojkovsky T, LoGrasso P, Kamenecka TM. Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3344-7. Epub 2009 Mar 26. PMID:19433357 doi:10.1016/j.bmcl.2009.03.086