1ta6
From Proteopedia
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[[Image:1ta6.png|left|200px]] | [[Image:1ta6.png|left|200px]] | ||
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{{STRUCTURE_1ta6| PDB=1ta6 | SCENE= }} | {{STRUCTURE_1ta6| PDB=1ta6 | SCENE= }} | ||
===Crystal structure of thrombin in complex with compound 14b=== | ===Crystal structure of thrombin in complex with compound 14b=== | ||
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{{ABSTRACT_PUBMED_9703466}} | {{ABSTRACT_PUBMED_9703466}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1ta6]] is a 2 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TA6 OCA]. | + | [[1ta6]] is a 2 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TA6 OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Hirudin]] | + | *[[Hirudin|Hirudin]] |
| + | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:009703466</ref><references group="xtra"/> |
| + | [[Category: Hirudo medicinalis]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: Yan, Y.]] | [[Category: Yan, Y.]] | ||
[[Category: Blood clotting]] | [[Category: Blood clotting]] | ||
| - | [[Category: Hydrolase | + | [[Category: Hydrolase]] |
| + | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Thrombin inhibitor complex]] | [[Category: Thrombin inhibitor complex]] | ||
Revision as of 00:31, 26 July 2012
Contents |
Crystal structure of thrombin in complex with compound 14b
Template:ABSTRACT PUBMED 9703466
About this Structure
1ta6 is a 2 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Tucker TJ, Brady SF, Lumma WC, Lewis SD, Gardell SJ, Naylor-Olsen AM, Yan Y, Sisko JT, Stauffer KJ, Lucas BJ, Lynch JJ, Cook JJ, Stranieri MT, Holahan MA, Lyle EA, Baskin EP, Chen IW, Dancheck KB, Krueger JA, Cooper CM, Vacca JP. Design and synthesis of a series of potent and orally bioavailable noncovalent thrombin inhibitors that utilize nonbasic groups in the P1 position. J Med Chem. 1998 Aug 13;41(17):3210-9. PMID:9703466 doi:http://dx.doi.org/10.1021/jm9801713
Categories: Hirudo medicinalis | Homo sapiens | Thrombin | Baskin, E P. | Brady, S F. | Chen, I W. | Cook, J J. | Cooper, C M. | Dancheck, K B. | Gardel, S J. | Holahan, M A. | Krueger, J A. | Lewis, S D. | Lucas, B Y. | Lumma, W C. | Lyle, E A. | Lynch, J J. | Naylor-Olsen, A M. | Sisko, J T. | Stauffer, K J. | Stranieri, M T. | Tucker, T J. | Vacca, J P. | Yan, Y. | Blood clotting | Hydrolase | Hydrolase-hydrolase inhibitor complex | Thrombin inhibitor complex
