1pq2
From Proteopedia
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[[Image:1pq2.png|left|200px]] | [[Image:1pq2.png|left|200px]] | ||
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{{STRUCTURE_1pq2| PDB=1pq2 | SCENE= }} | {{STRUCTURE_1pq2| PDB=1pq2 | SCENE= }} | ||
===Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8=== | ===Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Cytochrome P450]] | + | *[[Cytochrome P450|Cytochrome P450]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:014676196</ref><ref group="xtra">PMID:016086027</ref><ref group="xtra">PMID:016215230</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Unspecific monooxygenase]] | [[Category: Unspecific monooxygenase]] | ||
Revision as of 00:45, 26 July 2012
Contents |
Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8
Template:ABSTRACT PUBMED 14676196
About this Structure
1pq2 is a 2 chain structure of Cytochrome P450 with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Schoch GA, Yano JK, Wester MR, Griffin KJ, Stout CD, Johnson EF. Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site. J Biol Chem. 2004 Mar 5;279(10):9497-503. Epub 2003 Dec 15. PMID:14676196 doi:10.1074/jbc.M312516200
- Yano JK, Hsu MH, Griffin KJ, Stout CD, Johnson EF. Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen. Nat Struct Mol Biol. 2005 Sep;12(9):822-3. Epub 2005 Aug 7. PMID:16086027 doi:http://dx.doi.org/10.1038/nsmb971
- Wu ZL, Podust LM, Guengerich FP. Expansion of substrate specificity of cytochrome P450 2A6 by random and site-directed mutagenesis. J Biol Chem. 2005 Dec 9;280(49):41090-100. Epub 2005 Oct 7. PMID:16215230 doi:10.1074/jbc.M508182200
