3ii6

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{{Seed}}
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[[Image:3ii6.png|left|200px]]
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[[Image:3ii6.jpg|left|200px]]
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{{STRUCTURE_3ii6| PDB=3ii6 | SCENE= }}
{{STRUCTURE_3ii6| PDB=3ii6 | SCENE= }}
===Structure of human Xrcc4 in complex with the tandem BRCT domains of DNA LigaseIV.===
===Structure of human Xrcc4 in complex with the tandem BRCT domains of DNA LigaseIV.===
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{{ABSTRACT_PUBMED_19332554}}
{{ABSTRACT_PUBMED_19332554}}
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==Disease==
 
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Known disease associated with this structure: LIG4 syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601837 601837]], Multiple myeloma, resistance to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601837 601837]]
 
==About this Structure==
==About this Structure==
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3II6 is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3II6 OCA].
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[[3ii6]] is a 6 chain structure of [[DNA ligase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3II6 OCA].
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==See Also==
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*[[DNA ligase|DNA ligase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:19332554</ref><references group="xtra"/>
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<ref group="xtra">PMID:019332554</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Junop, M.]]
[[Category: Junop, M.]]
[[Category: Meesala, S.]]
[[Category: Meesala, S.]]
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[[Category: Alternative splicing]]
 
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Brct]]
[[Category: Brct]]
[[Category: Cell cycle]]
[[Category: Cell cycle]]
[[Category: Cell division]]
[[Category: Cell division]]
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[[Category: Coiled coil]]
 
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Dna damage]]
[[Category: Dna damage]]
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[[Category: Isopeptide bond]]
[[Category: Isopeptide bond]]
[[Category: Ligase]]
[[Category: Ligase]]
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[[Category: Ligase/dna binding protein complex]]
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[[Category: Ligase-dna binding protein complex]]
[[Category: Magnesium]]
[[Category: Magnesium]]
[[Category: Metal-binding]]
[[Category: Metal-binding]]
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[[Category: Nucleus]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
 
[[Category: Scid]]
[[Category: Scid]]
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[[Category: Ubl conjugation]]
 
[[Category: Xrcc4]]
[[Category: Xrcc4]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 12 13:49:35 2009''
 

Revision as of 01:12, 26 July 2012

Template:STRUCTURE 3ii6

Contents

Structure of human Xrcc4 in complex with the tandem BRCT domains of DNA LigaseIV.

Template:ABSTRACT PUBMED 19332554

About this Structure

3ii6 is a 6 chain structure of DNA ligase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Wu PY, Frit P, Meesala S, Dauvillier S, Modesti M, Andres SN, Huang Y, Sekiguchi J, Calsou P, Salles B, Junop MS. Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4. Mol Cell Biol. 2009 Jun;29(11):3163-72. Epub 2009 Mar 30. PMID:19332554 doi:10.1128/MCB.01895-08

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