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2gq2

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[[Image:2gq2.png|left|200px]]
[[Image:2gq2.png|left|200px]]
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{{STRUCTURE_2gq2| PDB=2gq2 | SCENE= }}
{{STRUCTURE_2gq2| PDB=2gq2 | SCENE= }}
===Mycobacterium tuberculosis ThyX-NADP complex===
===Mycobacterium tuberculosis ThyX-NADP complex===
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{{ABSTRACT_PUBMED_16730023}}
{{ABSTRACT_PUBMED_16730023}}
==About this Structure==
==About this Structure==
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[[2gq2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQ2 OCA].
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[[2gq2]] is a 4 chain structure of [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQ2 OCA].
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==See Also==
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*[[Thymidylate synthase|Thymidylate synthase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:16730023</ref><ref group="xtra">PMID:16139296</ref><references group="xtra"/>
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<ref group="xtra">PMID:016730023</ref><ref group="xtra">PMID:016139296</ref><references group="xtra"/>
[[Category: Mycobacterium tuberculosis h37rv]]
[[Category: Mycobacterium tuberculosis h37rv]]
[[Category: Hol, W G.]]
[[Category: Hol, W G.]]

Revision as of 01:36, 26 July 2012

Image:2gq2.png

Template:STRUCTURE 2gq2

Contents

Mycobacterium tuberculosis ThyX-NADP complex

Template:ABSTRACT PUBMED 16730023

About this Structure

2gq2 is a 4 chain structure of Thymidylate synthase with sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.

See Also

Reference

  • Sampathkumar P, Turley S, Sibley CH, Hol WG. NADP+ expels both the co-factor and a substrate analog from the Mycobacterium tuberculosis ThyX active site: opportunities for anti-bacterial drug design. J Mol Biol. 2006 Jun 30;360(1):1-6. Epub 2006 May 12. PMID:16730023 doi:10.1016/j.jmb.2006.04.061
  • Sampathkumar P, Turley S, Ulmer JE, Rhie HG, Sibley CH, Hol WG. Structure of the Mycobacterium tuberculosis flavin dependent thymidylate synthase (MtbThyX) at 2.0A resolution. J Mol Biol. 2005 Oct 7;352(5):1091-104. PMID:16139296 doi:10.1016/j.jmb.2005.07.071

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