2a07

(Difference between revisions)

Revision as of 01:44, 26 July 2012

2a07, resolution 1.90Å ()

Ligands:

Gene:

FOXP2, CAGH44, TNRC10 (Homo sapiens)

Structural annotation:
Resources:	InterPro : Ipr001766, Ipr015880, Ipr011991, Ipr007087 Pfam : PF00250 UniProt : O15409

Functional annotation:
Cellular component:	intracellular nucleus
Biological process:	transcription putamen development regulation of transcription, DNA-dependent caudate nucleus development
Molecular function:	sequence-specific DNA binding metal ion binding zinc ion binding protein homodimerization activity transcription factor activity nucleic acid binding DNA binding

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Caveats,

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

2a07 is a 10 chain structure of Forkhead box protein with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Stroud JC, Wu Y, Bates DL, Han A, Nowick K, Paabo S, Tong H, Chen L. Structure of the forkhead domain of FOXP2 bound to DNA. Structure. 2006 Jan;14(1):159-66. PMID:16407075 doi:10.1016/j.str.2005.10.005

@@ Line 1: / Line 1: @@
 [[Image:2a07.png|left|200px]]
-<!--
-The line below this paragraph, containing "STRUCTURE_2a07", creates the "Structure Box" on the page.
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-or leave the SCENE parameter empty for the default display.
--->
 {{STRUCTURE_2a07|  PDB=2a07  |  SCENE=  }}
 ===Crystal Structure of Foxp2 bound Specifically to DNA.===
-<!--
-The line below this paragraph, {{ABSTRACT_PUBMED_16407075}}, adds the Publication Abstract to the page
-(as it appears on PubMed at http://www.pubmed.gov), where 16407075 is the PubMed ID number.
--->
 {{ABSTRACT_PUBMED_16407075}}