1nwe

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[[Image:1nwe.png|left|200px]]
[[Image:1nwe.png|left|200px]]
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{{STRUCTURE_1nwe| PDB=1nwe | SCENE= }}
{{STRUCTURE_1nwe| PDB=1nwe | SCENE= }}
===Ptp1B R47C Modified at C47 with N-[4-(2-{2-[3-(2-Bromo-acetylamino)-propionylamino]-3-hydroxy-propionylamino}-ethyl)-phenyl]-oxalamic acid===
===Ptp1B R47C Modified at C47 with N-[4-(2-{2-[3-(2-Bromo-acetylamino)-propionylamino]-3-hydroxy-propionylamino}-ethyl)-phenyl]-oxalamic acid===
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{{ABSTRACT_PUBMED_12733877}}
{{ABSTRACT_PUBMED_12733877}}
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==Disease==
 
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Known disease associated with this structure: Insulin resistance, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176885 176885]]
 
==About this Structure==
==About this Structure==
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1NWE is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NWE OCA].
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[[1nwe]] is a 1 chain structure of [[Proten tyrosine phosphatase]] and [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NWE OCA].
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==See Also==
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*[[Proten tyrosine phosphatase|Proten tyrosine phosphatase]]
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*[[Tyrosine phosphatase|Tyrosine phosphatase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:12733877</ref><references group="xtra"/>
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<ref group="xtra">PMID:012733877</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
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[[Category: Simmons, R L.]]
[[Category: Simmons, R L.]]
[[Category: Waight, A.]]
[[Category: Waight, A.]]
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[[Category: Acetylation]]
 
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Phospatase]]
[[Category: Phospatase]]
[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
[[Category: Phosphotyrosine mimetic]]
[[Category: Phosphotyrosine mimetic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:03:31 2009''
 

Revision as of 01:51, 26 July 2012

Template:STRUCTURE 1nwe

Contents

Ptp1B R47C Modified at C47 with N-[4-(2-{2-[3-(2-Bromo-acetylamino)-propionylamino]-3-hydroxy-propionylamino}-ethyl)-phenyl]-oxalamic acid

Template:ABSTRACT PUBMED 12733877

About this Structure

1nwe is a 1 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Erlanson DA, McDowell RS, He MM, Randal M, Simmons RL, Kung J, Waight A, Hansen SK. Discovery of a new phosphotyrosine mimetic for PTP1B using breakaway tethering. J Am Chem Soc. 2003 May 14;125(19):5602-3. PMID:12733877 doi:10.1021/ja034440c

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