1t32
From Proteopedia
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[[Image:1t32.png|left|200px]] | [[Image:1t32.png|left|200px]] | ||
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{{STRUCTURE_1t32| PDB=1t32 | SCENE= }} | {{STRUCTURE_1t32| PDB=1t32 | SCENE= }} | ||
===A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation=== | ===A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation=== | ||
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==See Also== | ==See Also== | ||
| - | *[[Cathepsin]] | + | *[[Cathepsin|Cathepsin]] |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015741158</ref><ref group="xtra">PMID:008896442</ref><references group="xtra"/> |
[[Category: Cathepsin G]] | [[Category: Cathepsin G]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Revision as of 02:01, 26 July 2012
Contents |
A Dual Inhibitor of the Leukocyte Proteases Cathepsin G and Chymase with Therapeutic Efficacy in Animals Models of Inflammation
Template:ABSTRACT PUBMED 15741158
About this Structure
1t32 is a 1 chain structure of Cathepsin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- de Garavilla L, Greco MN, Sukumar N, Chen ZW, Pineda AO, Mathews FS, Di Cera E, Giardino EC, Wells GI, Haertlein BJ, Kauffman JA, Corcoran TW, Derian CK, Eckardt AJ, Damiano BP, Andrade-Gordon P, Maryanoff BE. A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo. J Biol Chem. 2005 May 6;280(18):18001-7. Epub 2005 Feb 28. PMID:15741158 doi:10.1074/jbc.M501302200
- Hof P, Mayr I, Huber R, Korzus E, Potempa J, Travis J, Powers JC, Bode W. The 1.8 A crystal structure of human cathepsin G in complex with Suc-Val-Pro-PheP-(OPh)2: a Janus-faced proteinase with two opposite specificities. EMBO J. 1996 Oct 15;15(20):5481-91. PMID:8896442
Categories: Cathepsin G | Homo sapiens | Abraham, W M. | Andrade-Gordon, P. | Cera, E Di. | Chen, Z. | Corcoran, T W. | Damiano, B P. | Derian, C K. | Eckardt, A J. | Garavilla, L de. | Giardino, E C. | Greco, M N. | Haertlein, B J. | Kauffman, J A. | Maryanoff, B E. | Mathews, F S. | Pineda, A O. | Sukumar, N. | Wells, G I. | Hydrolase | Inflammation inhibitor serine protease
