2brh
From Proteopedia
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{{STRUCTURE_2brh| PDB=2brh | SCENE= }} | {{STRUCTURE_2brh| PDB=2brh | SCENE= }} | ||
===STRUCTURE-BASED DESIGN OF NOVEL CHK1 INHIBITORS: INSIGHTS INTO HYDROGEN BONDING AND PROTEIN-LIGAND AFFINITY=== | ===STRUCTURE-BASED DESIGN OF NOVEL CHK1 INHIBITORS: INSIGHTS INTO HYDROGEN BONDING AND PROTEIN-LIGAND AFFINITY=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2brh]] is a 1 chain structure of [[Serine/threonine protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BRH OCA]. | |
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| + | ==See Also== | ||
| + | *[[Serine/threonine protein kinase|Serine/threonine protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015974586</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Oncology]] | [[Category: Oncology]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
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[[Category: Pyrrolopyrimidine]] | [[Category: Pyrrolopyrimidine]] | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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Revision as of 02:19, 26 July 2012
Contents |
STRUCTURE-BASED DESIGN OF NOVEL CHK1 INHIBITORS: INSIGHTS INTO HYDROGEN BONDING AND PROTEIN-LIGAND AFFINITY
Template:ABSTRACT PUBMED 15974586
About this Structure
2brh is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Foloppe N, Fisher LM, Howes R, Kierstan P, Potter A, Robertson AG, Surgenor AE. Structure-based design of novel Chk1 inhibitors: insights into hydrogen bonding and protein-ligand affinity. J Med Chem. 2005 Jun 30;48(13):4332-45. PMID:15974586 doi:10.1021/jm049022c
Categories: Homo sapiens | Non-specific serine/threonine protein kinase | Fisher, L M. | Foloppe, N. | Howes, R. | Kierstan, P. | Potter, A. | Robertson, A G.S. | Surgenor, A E. | Atp-binding | Cell cycle | Dna damage | Drug design | Furanopyrimidine | Kinase | Molecular recognition | Nuclear protein | Oncology | Phosphorylation | Pyrrolopyrimidine | Serine/threonine-protein kinase | Transferase
