2r0u
From Proteopedia
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{{STRUCTURE_2r0u| PDB=2r0u | SCENE= }} | {{STRUCTURE_2r0u| PDB=2r0u | SCENE= }} | ||
===Crystal Structure of Chek1 in Complex with Inhibitor 54=== | ===Crystal Structure of Chek1 in Complex with Inhibitor 54=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2r0u]] is a 1 chain structure of [[Serine/threonine protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0U OCA]. | |
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| + | ==See Also== | ||
| + | *[[Serine/threonine protein kinase|Serine/threonine protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017900896</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: Cell cycle check point]] | [[Category: Cell cycle check point]] | ||
[[Category: Chek1]] | [[Category: Chek1]] | ||
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[[Category: Dna damage]] | [[Category: Dna damage]] | ||
[[Category: Dna repair]] | [[Category: Dna repair]] | ||
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[[Category: Nucleus]] | [[Category: Nucleus]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
| - | [[Category: Polymorphism]] | ||
[[Category: Serine/threonine-protein kinase]] | [[Category: Serine/threonine-protein kinase]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
| - | [[Category: Ubl conjugation]] | ||
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Revision as of 02:19, 26 July 2012
Contents |
Crystal Structure of Chek1 in Complex with Inhibitor 54
Template:ABSTRACT PUBMED 17900896
About this Structure
2r0u is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Garbaccio RM, Huang S, Tasber ES, Fraley ME, Yan Y, Munshi S, Ikuta M, Kuo L, Kreatsoulas C, Stirdivant S, Drakas B, Rickert K, Walsh ES, Hamilton KA, Buser CA, Hardwick J, Mao X, Beck SC, Abrams MT, Tao W, Lobell R, Sepp-Lorenzino L, Hartman GD. Synthesis and evaluation of substituted benzoisoquinolinones as potent inhibitors of Chk1 kinase. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6280-5. Epub 2007 Sep 7. PMID:17900896 doi:10.1016/j.bmcl.2007.09.007
