2oht

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Revision as of 02:49, 26 July 2012

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Template:STRUCTURE 2oht

Contents 1 X-ray crystal structure of beta secretase complexed with compound 7 2 About this Structure 3 See Also 4 Reference

X-ray crystal structure of beta secretase complexed with compound 7

Template:ABSTRACT PUBMED 17315857

About this Structure

2oht is a 1 chain structure of Beta secretase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Beta secretase

Reference

• Congreve M, Aharony D, Albert J, Callaghan O, Campbell J, Carr RA, Chessari G, Cowan S, Edwards PD, Frederickson M, McMenamin R, Murray CW, Patel S, Wallis N. Application of fragment screening by X-ray crystallography to the discovery of aminopyridines as inhibitors of beta-secretase. J Med Chem. 2007 Mar 22;50(6):1124-32. Epub 2007 Feb 22. PMID:17315857 doi:10.1021/jm061197u