3ben
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
[[Image:3ben.png|left|200px]] | [[Image:3ben.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3ben", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3ben| PDB=3ben | SCENE= }} | {{STRUCTURE_3ben| PDB=3ben | SCENE= }} | ||
===Structure of N-(12-imidazolyl-dodecanoyl)-L-leucine inhibitor bound to the heme domain of Cytochrome P450-BM3=== | ===Structure of N-(12-imidazolyl-dodecanoyl)-L-leucine inhibitor bound to the heme domain of Cytochrome P450-BM3=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_18298086}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 18298086 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_18298086}} | {{ABSTRACT_PUBMED_18298086}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3ben]] is a 2 chain structure of [[Cytochrome P450]] and [[NADPH-Cytochrome P450 Reductase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BEN OCA]. | + | [[3ben]] is a 2 chain structure of [[Cytochrome P450]], [[Flavocytochrome]] and [[NADPH-Cytochrome P450 Reductase]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BEN OCA]. |
==See Also== | ==See Also== | ||
| - | *[[Cytochrome P450]] | + | *[[Cytochrome P450|Cytochrome P450]] |
| - | *[[NADPH-Cytochrome P450 Reductase]] | + | *[[Flavocytochrome|Flavocytochrome]] |
| + | *[[NADPH-Cytochrome P450 Reductase|NADPH-Cytochrome P450 Reductase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018298086</ref><ref group="xtra">PMID:011695892</ref><ref group="xtra">PMID:009843385</ref><references group="xtra"/> |
[[Category: Bacillus megaterium]] | [[Category: Bacillus megaterium]] | ||
[[Category: Unspecific monooxygenase]] | [[Category: Unspecific monooxygenase]] | ||
Revision as of 02:51, 26 July 2012
Contents |
Structure of N-(12-imidazolyl-dodecanoyl)-L-leucine inhibitor bound to the heme domain of Cytochrome P450-BM3
Template:ABSTRACT PUBMED 18298086
About this Structure
3ben is a 2 chain structure of Cytochrome P450, Flavocytochrome and NADPH-Cytochrome P450 Reductase with sequence from Bacillus megaterium. Full crystallographic information is available from OCA.
See Also
Reference
- Haines DC, Chen B, Tomchick DR, Bondlela M, Hegde A, Machius M, Peterson JA. Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel. Biochemistry. 2008 Mar 25;47(12):3662-70. Epub 2008 Feb 26. PMID:18298086 doi:10.1021/bi7023964
- Haines DC, Tomchick DR, Machius M, Peterson JA. Pivotal role of water in the mechanism of P450BM-3. Biochemistry. 2001 Nov 13;40(45):13456-65. PMID:11695892
- Noble MA, Quaroni L, Chumanov GD, Turner KL, Chapman SK, Hanzlik RP, Munro AW. Imidazolyl carboxylic acids as mechanistic probes of flavocytochrome P-450 BM3. Biochemistry. 1998 Nov 10;37(45):15799-807. PMID:9843385 doi:10.1021/bi980462d
