2fix
From Proteopedia
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[[Image:2fix.png|left|200px]] | [[Image:2fix.png|left|200px]] | ||
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{{STRUCTURE_2fix| PDB=2fix | SCENE= }} | {{STRUCTURE_2fix| PDB=2fix | SCENE= }} | ||
===Structure of human liver FBPase complexed with potent benzoxazole allosteric inhibitiors=== | ===Structure of human liver FBPase complexed with potent benzoxazole allosteric inhibitiors=== | ||
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{{ABSTRACT_PUBMED_16446092}} | {{ABSTRACT_PUBMED_16446092}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[2fix]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIX OCA]. | + | [[2fix]] is a 4 chain structure of [[Fructose-1%2C6-bisphosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIX OCA]. |
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| + | ==See Also== | ||
| + | *[[Fructose-1%2C6-bisphosphatase|Fructose-1%2C6-bisphosphatase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016446092</ref><ref group="xtra">PMID:016442285</ref><references group="xtra"/> |
[[Category: Fructose-bisphosphatase]] | [[Category: Fructose-bisphosphatase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
Revision as of 03:05, 26 July 2012
Contents |
Structure of human liver FBPase complexed with potent benzoxazole allosteric inhibitiors
Template:ABSTRACT PUBMED 16446092
About this Structure
2fix is a 4 chain structure of Fructose-1,6-bisphosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Lai C, Gum RJ, Daly M, Fry EH, Hutchins C, Abad-Zapatero C, von Geldern TW. Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1807-10. Epub 2006 Jan 30. PMID:16446092 doi:10.1016/j.bmcl.2006.01.014
- von Geldern TW, Lai C, Gum RJ, Daly M, Sun C, Fry EH, Abad-Zapatero C. Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1811-5. Epub 2006 Jan 25. PMID:16442285 doi:10.1016/j.bmcl.2006.01.015
