2k9r

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[[Image:2k9r.png|left|200px]]
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{{STRUCTURE_2k9r| PDB=2k9r | SCENE= }}
{{STRUCTURE_2k9r| PDB=2k9r | SCENE= }}
===Enhancing the activity of insulin by stereospecific unfolding===
===Enhancing the activity of insulin by stereospecific unfolding===
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{{ABSTRACT_PUBMED_19321436}}
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==Disease==
 
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Known disease associated with this structure: Hyperproinsulinemia, familial, with or without diabetes OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176730 176730]]
 
==About this Structure==
==About this Structure==
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2K9R is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9R OCA].
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[[2k9r]] is a 2 chain structure of [[Molecular Playground/Insulin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K9R OCA].
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==See Also==
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*[[Molecular Playground/Insulin|Molecular Playground/Insulin]]
==Reference==
==Reference==
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<ref group="xtra">PMID:19321436</ref><references group="xtra"/>
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<ref group="xtra">PMID:019321436</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hu, S Q.]]
[[Category: Hu, S Q.]]
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[[Category: Insulin]]
[[Category: Insulin]]
[[Category: Mutant]]
[[Category: Mutant]]
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[[Category: Pharmaceutical]]
 
[[Category: Secreted]]
[[Category: Secreted]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 10 16:32:05 2009''
 

Revision as of 03:34, 26 July 2012

Image:2k9r.png

Template:STRUCTURE 2k9r

Contents

Enhancing the activity of insulin by stereospecific unfolding

Template:ABSTRACT PUBMED 19321436

About this Structure

2k9r is a 2 chain structure of Molecular Playground/Insulin with sequence from Homo sapiens. Full experimental information is available from OCA.

See Also

Reference

  • Hua QX, Xu B, Huang K, Hu SQ, Nakagawa S, Jia W, Wang S, Whittaker J, Katsoyannis PG, Weiss MA. Enhancing the activity of a protein by stereospecific unfolding: conformational life cycle of insulin and its evolutionary origins. J Biol Chem. 2009 May 22;284(21):14586-96. Epub 2009 Mar 25. PMID:19321436 doi:10.1074/jbc.M900085200

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