1qad

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Revision as of 03:39, 26 July 2012

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Template:STRUCTURE 1qad

Contents 1 Crystal Structure of the C-Terminal SH2 Domain of the P85 alpha Regulatory Subunit of Phosphoinositide 3-Kinase: An SH2 domain mimicking its own substrate 2 About this Structure 3 See Also 4 Reference

Crystal Structure of the C-Terminal SH2 Domain of the P85 alpha Regulatory Subunit of Phosphoinositide 3-Kinase: An SH2 domain mimicking its own substrate

Template:ABSTRACT PUBMED 10525402

About this Structure

1qad is a 1 chain structure of Phosphoinositide 3-Kinases with sequence from Bos taurus. Full crystallographic information is available from OCA.

See Also

• Phosphoinositide 3-Kinases

Reference

• Hoedemaeker FJ, Siegal G, Roe SM, Driscoll PC, Abrahams JP. Crystal structure of the C-terminal SH2 domain of the p85alpha regulatory subunit of phosphoinositide 3-kinase: an SH2 domain mimicking its own substrate. J Mol Biol. 1999 Oct 1;292(4):763-70. PMID:10525402 doi:http://dx.doi.org/10.1006/jmbi.1999.3111
• Ching TT, Lin HP, Yang CC, Oliveira M, Lu PJ, Chen CS. Specific binding of the C-terminal Src homology 2 domain of the p85alpha subunit of phosphoinositide 3-kinase to phosphatidylinositol 3,4,5-trisphosphate. Localization and engineering of the phosphoinositide-binding motif. J Biol Chem. 2001 Nov 23;276(47):43932-8. Epub 2001 Sep 12. PMID:11555646 doi:10.1074/jbc.M105159200