1owh

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[[Image:1owh.png|left|200px]]
[[Image:1owh.png|left|200px]]
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{{STRUCTURE_1owh| PDB=1owh | SCENE= }}
{{STRUCTURE_1owh| PDB=1owh | SCENE= }}
===Substituted 2-Naphthamidine Inhibitors of Urokinase===
===Substituted 2-Naphthamidine Inhibitors of Urokinase===
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{{ABSTRACT_PUBMED_14711304}}
{{ABSTRACT_PUBMED_14711304}}
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==Disease==
 
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Known disease associated with this structure: Alzheimer disease, late-onset, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191840 191840]]
 
==About this Structure==
==About this Structure==
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1OWH is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OWH OCA].
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[[1owh]] is a 1 chain structure of [[Urokinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OWH OCA].
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==See Also==
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*[[Urokinase|Urokinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:14711304</ref><references group="xtra"/>
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<ref group="xtra">PMID:014711304</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: U-plasminogen activator]]
[[Category: U-plasminogen activator]]
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[[Category: Plasminogen activation]]
[[Category: Plasminogen activation]]
[[Category: Serine protease]]
[[Category: Serine protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:49:44 2009''
 

Revision as of 03:40, 26 July 2012

Image:1owh.png

Template:STRUCTURE 1owh

Contents

Substituted 2-Naphthamidine Inhibitors of Urokinase

Template:ABSTRACT PUBMED 14711304

About this Structure

1owh is a 1 chain structure of Urokinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Wendt MD, Rockway TW, Geyer A, McClellan W, Weitzberg M, Zhao X, Mantei R, Nienaber VL, Stewart K, Klinghofer V, Giranda VL. Identification of novel binding interactions in the development of potent, selective 2-naphthamidine inhibitors of urokinase. Synthesis, structural analysis, and SAR of N-phenyl amide 6-substitution. J Med Chem. 2004 Jan 15;47(2):303-24. PMID:14711304 doi:10.1021/jm0300072

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