1tq0

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Revision as of 03:55, 26 July 2012

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Template:STRUCTURE 1tq0

Contents 1 Crystal structure of the potent anticoagulant thrombin mutant W215A/E217A in free form 2 About this Structure 3 See Also 4 Reference

Crystal structure of the potent anticoagulant thrombin mutant W215A/E217A in free form

Template:ABSTRACT PUBMED 15252033

About this Structure

1tq0 is a 4 chain structure of Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Thrombin

Reference

• Pineda AO, Chen ZW, Caccia S, Cantwell AM, Savvides SN, Waksman G, Mathews FS, Di Cera E. The anticoagulant thrombin mutant W215A/E217A has a collapsed primary specificity pocket. J Biol Chem. 2004 Sep 17;279(38):39824-8. Epub 2004 Jul 13. PMID:15252033 doi:http://dx.doi.org/10.1074/jbc.M407272200
• Nguyen DM, Leila Reynald R, Gittis AG, Lattman EE. X-ray and thermodynamic studies of staphylococcal nuclease variants I92E and I92K: insights into polarity of the protein interior. J Mol Biol. 2004 Aug 6;341(2):565-74. PMID:15276844 doi:10.1016/j.jmb.2004.05.066