3byu

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[[Image:3byu.png|left|200px]]
[[Image:3byu.png|left|200px]]
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{{STRUCTURE_3byu| PDB=3byu | SCENE= }}
{{STRUCTURE_3byu| PDB=3byu | SCENE= }}
===co-crystal structure of Lck and aminopyrimidine reverse amide 23===
===co-crystal structure of Lck and aminopyrimidine reverse amide 23===
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{{ABSTRACT_PUBMED_18321037}}
{{ABSTRACT_PUBMED_18321037}}
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==Disease==
 
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Known disease associated with this structure: SCID due to LCK deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=153390 153390]]
 
==About this Structure==
==About this Structure==
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3BYU is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BYU OCA].
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[[3byu]] is a 1 chain structure of [[Proto-oncogene tyrosine-protein kinase]] and [[Tyrosine kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BYU OCA].
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==See Also==
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*[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]]
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*[[Tyrosine kinase|Tyrosine kinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18321037</ref><references group="xtra"/>
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<ref group="xtra">PMID:018321037</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Huang, X.]]
[[Category: Huang, X.]]
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[[Category: Alternative splicing]]
 
[[Category: Atp-binding]]
[[Category: Atp-binding]]
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[[Category: Chromosomal rearrangement]]
 
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[[Category: Cytoplasm]]
 
[[Category: Disease mutation]]
[[Category: Disease mutation]]
[[Category: Host-virus interaction]]
[[Category: Host-virus interaction]]
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[[Category: Transferase]]
[[Category: Transferase]]
[[Category: Tyrosine-protein kinase]]
[[Category: Tyrosine-protein kinase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:12:21 2009''
 

Revision as of 04:33, 26 July 2012

Image:3byu.png

Template:STRUCTURE 3byu

Contents

co-crystal structure of Lck and aminopyrimidine reverse amide 23

Template:ABSTRACT PUBMED 18321037

About this Structure

3byu is a 1 chain structure of Proto-oncogene tyrosine-protein kinase and Tyrosine kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • DiMauro EF, Newcomb J, Nunes JJ, Bemis JE, Boucher C, Chai L, Chaffee SC, Deak HL, Epstein LF, Faust T, Gallant P, Gore A, Gu Y, Henkle B, Hsieh F, Huang X, Kim JL, Lee JH, Martin MW, McGowan DC, Metz D, Mohn D, Morgenstern KA, Oliveira-dos-Santos A, Patel VF, Powers D, Rose PE, Schneider S, Tomlinson SA, Tudor YY, Turci SM, Welcher AA, Zhao H, Zhu L, Zhu X. Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation. J Med Chem. 2008 Mar 27;51(6):1681-94. Epub 2008 Mar 6. PMID:18321037 doi:10.1021/jm7010996

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OCA

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