1qbv
From Proteopedia
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[[Image:1qbv.png|left|200px]] | [[Image:1qbv.png|left|200px]] | ||
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{{STRUCTURE_1qbv| PDB=1qbv | SCENE= }} | {{STRUCTURE_1qbv| PDB=1qbv | SCENE= }} | ||
===CRYSTAL STRUCTURE OF THROMBIN COMPLEXED WITH AN GUANIDINE-MIMETIC INHIBITOR=== | ===CRYSTAL STRUCTURE OF THROMBIN COMPLEXED WITH AN GUANIDINE-MIMETIC INHIBITOR=== | ||
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{{ABSTRACT_PUBMED_9622548}} | {{ABSTRACT_PUBMED_9622548}} | ||
==About this Structure== | ==About this Structure== | ||
- | [[1qbv]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/ | + | [[1qbv]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QBV OCA]. |
==See Also== | ==See Also== | ||
- | *[[Hirudin]] | + | *[[Hirudin|Hirudin]] |
+ | *[[Thrombin|Thrombin]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:009622548</ref><references group="xtra"/> |
- | [[Category: | + | [[Category: Hirudo medicinalis]] |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] | ||
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[[Category: 3dp]] | [[Category: 3dp]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
+ | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Thrombin]] | [[Category: Thrombin]] |
Revision as of 04:41, 26 July 2012
Contents |
CRYSTAL STRUCTURE OF THROMBIN COMPLEXED WITH AN GUANIDINE-MIMETIC INHIBITOR
Template:ABSTRACT PUBMED 9622548
About this Structure
1qbv is a 3 chain structure of Hirudin and Thrombin with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Bone R, Lu T, Illig CR, Soll RM, Spurlino JC. Structural analysis of thrombin complexed with potent inhibitors incorporating a phenyl group as a peptide mimetic and aminopyridines as guanidine substitutes. J Med Chem. 1998 Jun 4;41(12):2068-75. PMID:9622548 doi:10.1021/jm970796l