1cz2
From Proteopedia
(New page: 200px<br /><applet load="1cz2" size="450" color="white" frame="true" align="right" spinBox="true" caption="1cz2" /> '''SOLUTION STRUCTURE OF WHEAT NS-LTP COMPLEXED...) |
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| - | [[Image:1cz2.jpg|left|200px]]<br /><applet load="1cz2" size=" | + | [[Image:1cz2.jpg|left|200px]]<br /><applet load="1cz2" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1cz2" /> | caption="1cz2" /> | ||
'''SOLUTION STRUCTURE OF WHEAT NS-LTP COMPLEXED WITH PROSTAGLANDIN B2.'''<br /> | '''SOLUTION STRUCTURE OF WHEAT NS-LTP COMPLEXED WITH PROSTAGLANDIN B2.'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The 3D solution structure of wheat nonspecific lipid transfer protein | + | The 3D solution structure of wheat nonspecific lipid transfer protein (ns-LTP) complexed with prostaglandin B2, a lipid with both vinyl and hydroxylated groups, has been determined by 1H 2D NMR. The global fold of the protein is close to the previously published structures of wheat, maize, barley and rice ns-LTPs. The ligand is almost completely embedded in the hydrophobic core of the protein. Structure comparisons of free and bound wheat ns-LTP reveal that the binding of prostaglandin B2 hardly affects the global fold of the protein. The structural data on this unusual complex are discussed and compared with other known ns-LTP lipid-complexes. |
==About this Structure== | ==About this Structure== | ||
| - | 1CZ2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum] with E2P as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 1CZ2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum] with <scene name='pdbligand=E2P:'>E2P</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CZ2 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Triticum aestivum]] | [[Category: Triticum aestivum]] | ||
[[Category: Caille, A.]] | [[Category: Caille, A.]] | ||
| - | [[Category: Douliez, J | + | [[Category: Douliez, J P.]] |
[[Category: Marion, D.]] | [[Category: Marion, D.]] | ||
[[Category: Tassin-Moindrot, S.]] | [[Category: Tassin-Moindrot, S.]] | ||
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[[Category: protein complex alpha helix]] | [[Category: protein complex alpha helix]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:11:08 2008'' |
Revision as of 10:11, 21 February 2008
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SOLUTION STRUCTURE OF WHEAT NS-LTP COMPLEXED WITH PROSTAGLANDIN B2.
Overview
The 3D solution structure of wheat nonspecific lipid transfer protein (ns-LTP) complexed with prostaglandin B2, a lipid with both vinyl and hydroxylated groups, has been determined by 1H 2D NMR. The global fold of the protein is close to the previously published structures of wheat, maize, barley and rice ns-LTPs. The ligand is almost completely embedded in the hydrophobic core of the protein. Structure comparisons of free and bound wheat ns-LTP reveal that the binding of prostaglandin B2 hardly affects the global fold of the protein. The structural data on this unusual complex are discussed and compared with other known ns-LTP lipid-complexes.
About this Structure
1CZ2 is a Single protein structure of sequence from Triticum aestivum with as ligand. Full crystallographic information is available from OCA.
Reference
The wide binding properties of a wheat nonspecific lipid transfer protein. Solution structure of a complex with prostaglandin B2., Tassin-Moindrot S, Caille A, Douliez JP, Marion D, Vovelle F, Eur J Biochem. 2000 Feb;267(4):1117-24. PMID:10672021
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