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3ara
From Proteopedia
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[[Image:3ara.png|left|200px]] | [[Image:3ara.png|left|200px]] | ||
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===Discovery of Novel Uracil Derivatives as Potent Human dUTPase Inhibitors=== | ===Discovery of Novel Uracil Derivatives as Potent Human dUTPase Inhibitors=== | ||
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Revision as of 04:56, 26 July 2012
Contents |
Discovery of Novel Uracil Derivatives as Potent Human dUTPase Inhibitors
Template:ABSTRACT PUBMED 22404301
About this Structure
3ara is a 3 chain structure of Deoxyuridine 5'-triphosphate nucleotidohydrolase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Miyakoshi H, Miyahara S, Yokogawa T, Chong KT, Taguchi J, Endoh K, Yano W, Wakasa T, Ueno H, Takao Y, Nomura M, Shuto S, Nagasawa H, Fukuoka M. Synthesis and discovery of N-carbonylpyrrolidine- or N-sulfonylpyrrolidine-containing uracil derivatives as potent human deoxyuridine triphosphatase inhibitors. J Med Chem. 2012 Apr 12;55(7):2960-9. Epub 2012 Mar 26. PMID:22404301 doi:10.1021/jm201627n
