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1w22
From Proteopedia
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===CRYSTAL STRUCTURE OF INHIBITED HUMAN HDAC8=== | ===CRYSTAL STRUCTURE OF INHIBITED HUMAN HDAC8=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1w22]] is a 2 chain structure of [[Histone deacetylase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W22 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Histone deacetylase|Histone deacetylase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015477595</ref><ref group="xtra">PMID:019053282</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Casavola, E Caroli.]] | [[Category: Casavola, E Caroli.]] | ||
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[[Category: Nuclear protein]] | [[Category: Nuclear protein]] | ||
[[Category: Repressor]] | [[Category: Repressor]] | ||
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Revision as of 05:27, 26 July 2012
Contents |
CRYSTAL STRUCTURE OF INHIBITED HUMAN HDAC8
Template:ABSTRACT PUBMED 15477595
About this Structure
1w22 is a 2 chain structure of Histone deacetylase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Vannini A, Volpari C, Filocamo G, Casavola EC, Brunetti M, Renzoni D, Chakravarty P, Paolini C, De Francesco R, Gallinari P, Steinkuhler C, Di Marco S. Crystal structure of a eukaryotic zinc-dependent histone deacetylase, human HDAC8, complexed with a hydroxamic acid inhibitor. Proc Natl Acad Sci U S A. 2004 Oct 19;101(42):15064-9. Epub 2004 Oct 11. PMID:15477595
- Dowling DP, Gantt SL, Gattis SG, Fierke CA, Christianson DW. Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors. Biochemistry. 2008 Dec 23;47(51):13554-63. PMID:19053282 doi:10.1021/bi801610c
