1ads

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{{STRUCTURE_1ads| PDB=1ads | SCENE= }}
{{STRUCTURE_1ads| PDB=1ads | SCENE= }}
===AN UNLIKELY SUGAR SUBSTRATE SITE IN THE 1.65 ANGSTROMS STRUCTURE OF THE HUMAN ALDOSE REDUCTASE HOLOENZYME IMPLICATED IN DIABETIC COMPLICATIONS===
===AN UNLIKELY SUGAR SUBSTRATE SITE IN THE 1.65 ANGSTROMS STRUCTURE OF THE HUMAN ALDOSE REDUCTASE HOLOENZYME IMPLICATED IN DIABETIC COMPLICATIONS===
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{{ABSTRACT_PUBMED_1621098}}
{{ABSTRACT_PUBMED_1621098}}
==About this Structure==
==About this Structure==
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1ADS is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ADS OCA].
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[[1ads]] is a 1 chain structure of [[Aldose Reductase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ADS OCA].
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==See Also==
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*[[Aldose Reductase|Aldose Reductase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:1621098</ref><references group="xtra"/>
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<ref group="xtra">PMID:001621098</ref><ref group="xtra">PMID:007599122</ref><ref group="xtra">PMID:011917145</ref><ref group="xtra">PMID:012215419</ref><references group="xtra"/>
[[Category: Aldehyde reductase]]
[[Category: Aldehyde reductase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Wilson, D K.]]
[[Category: Wilson, D K.]]
[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:15:10 2009''
 

Revision as of 05:28, 26 July 2012

Image:1ads.png

Template:STRUCTURE 1ads

Contents

AN UNLIKELY SUGAR SUBSTRATE SITE IN THE 1.65 ANGSTROMS STRUCTURE OF THE HUMAN ALDOSE REDUCTASE HOLOENZYME IMPLICATED IN DIABETIC COMPLICATIONS

Template:ABSTRACT PUBMED 1621098

About this Structure

1ads is a 1 chain structure of Aldose Reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Wilson DK, Bohren KM, Gabbay KH, Quiocho FA. An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications. Science. 1992 Jul 3;257(5066):81-4. PMID:1621098
  • De Winter HL, von Itzstein M. Aldose reductase as a target for drug design: molecular modeling calculations on the binding of acyclic sugar substrates to the enzyme. Biochemistry. 1995 Jul 4;34(26):8299-308. PMID:7599122
  • Bhattacharyya R, Samanta U, Chakrabarti P. Aromatic-aromatic interactions in and around alpha-helices. Protein Eng. 2002 Feb;15(2):91-100. PMID:11917145
  • Ermolenko DN, Thomas ST, Aurora R, Gronenborn AM, Makhatadze GI. Hydrophobic interactions at the Ccap position of the C-capping motif of alpha-helices. J Mol Biol. 2002 Sep 6;322(1):123-35. PMID:12215419

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