1opc

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(New page: 200px<br /> <applet load="1opc" size="450" color="white" frame="true" align="right" spinBox="true" caption="1opc, resolution 1.95&Aring;" /> '''OMPR DNA-BINDING DO...)
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==About this Structure==
==About this Structure==
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1OPC is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1OPC OCA]].
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1OPC is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]]. Structure known Active Sites: ALP, RH and W1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1OPC OCA]].
==Reference==
==Reference==
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[[Category: winged helix]]
[[Category: winged helix]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 21:06:25 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:48:42 2007''

Revision as of 11:43, 30 October 2007


1opc, resolution 1.95Å

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OMPR DNA-BINDING DOMAIN, ESCHERICHIA COLI

Overview

BACKGROUND: The differential expression of the ompF and ompC genes is, regulated by two proteins that belong to the two component family of, signal transduction proteins: the histidine kinase, EnvZ, and the response, regulator, OmpR. OmpR belongs to a subfamily of at least 50 response, regulators with homologous C-terminal DNA-binding domains of approximately, 98 amino acids. Sequence homology with DNA-binding proteins of known, structure cannot be detected, and the lack of structural information has, prevented understanding of many of this familys functional properties., RESULTS: We have determined the crystal structure of the Escherichia coli, OmpR C-terminal domain at 1.95 A resolution. The structure consists of, three alpha helices packed against two antiparallel beta sheets. Two, ... [(full description)]

About this Structure

1OPC is a [Single protein] structure of sequence from [Escherichia coli]. Structure known Active Sites: ALP, RH and W1. Full crystallographic information is available from [OCA].

Reference

The DNA-binding domain of OmpR: crystal structures of a winged helix transcription factor., Martinez-Hackert E, Stock AM, Structure. 1997 Jan 15;5(1):109-24. PMID:9016718

Page seeded by OCA on Tue Oct 30 13:48:42 2007

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