2g72
From Proteopedia
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Contents |
Structure of hPNMT with inhibitor 3-fluoromethyl-7-thiomorpholinosulfonamide-THIQ and AdoMet
Template:ABSTRACT PUBMED 17845018
About this Structure
2g72 is a 2 chain structure of Phenylethanolamine N-methyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Gee CL, Drinkwater N, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Enzyme adaptation to inhibitor binding: a cryptic binding site in phenylethanolamine N-methyltransferase. J Med Chem. 2007 Oct 4;50(20):4845-53. Epub 2007 Sep 11. PMID:17845018 doi:10.1021/jm0703385