1vsn
From Proteopedia
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===Crystal structure of a potent small molecule inhibitor bound to cathepsin K=== | ===Crystal structure of a potent small molecule inhibitor bound to cathepsin K=== | ||
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{{ABSTRACT_PUBMED_16413777}} | {{ABSTRACT_PUBMED_16413777}} | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[1vsn]] is a 1 chain structure of [[Cathepsin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2fdz 2fdz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VSN OCA]. | |
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+ | ==See Also== | ||
+ | *[[Cathepsin|Cathepsin]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016413777</ref><references group="xtra"/> |
[[Category: Cathepsin K]] | [[Category: Cathepsin K]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: McGrath, M.]] | [[Category: McGrath, M.]] | ||
+ | [[Category: Hydrolase]] | ||
[[Category: Osteoporosis]] | [[Category: Osteoporosis]] | ||
[[Category: Proteae]] | [[Category: Proteae]] | ||
[[Category: Structure-guided drug design]] | [[Category: Structure-guided drug design]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 03:38:23 2009'' |
Revision as of 05:43, 26 July 2012
Contents |
Crystal structure of a potent small molecule inhibitor bound to cathepsin K
Template:ABSTRACT PUBMED 16413777
About this Structure
1vsn is a 1 chain structure of Cathepsin with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2fdz. Full crystallographic information is available from OCA.
See Also
Reference
- Li CS, Deschenes D, Desmarais S, Falgueyret JP, Gauthier JY, Kimmel DB, Leger S, Masse F, McGrath ME, McKay DJ, Percival MD, Riendeau D, Rodan SB, Therien M, Truong VL, Wesolowski G, Zamboni R, Black WC. Identification of a potent and selective non-basic cathepsin K inhibitor. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1985-9. Epub 2006 Jan 18. PMID:16413777 doi:10.1016/j.bmcl.2005.12.071