3bxq
From Proteopedia
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===The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition=== | ===The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3bxq]] is a 4 chain structure of [[Molecular Playground/Insulin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BXQ OCA]. | |
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| + | ==See Also== | ||
| + | *[[Molecular Playground/Insulin|Molecular Playground/Insulin]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:018332129</ref><ref group="xtra">PMID:018492668</ref><references group="xtra"/> |
[[Category: Hu, S Q.]] | [[Category: Hu, S Q.]] | ||
[[Category: Huang, K.]] | [[Category: Huang, K.]] | ||
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[[Category: Receptor binding]] | [[Category: Receptor binding]] | ||
[[Category: Tr transition]] | [[Category: Tr transition]] | ||
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Revision as of 06:01, 26 July 2012
Contents |
The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition
Template:ABSTRACT PUBMED 18332129
About this Structure
3bxq is a 4 chain structure of Molecular Playground/Insulin. Full crystallographic information is available from OCA.
See Also
Reference
- Hua QX, Nakagawa SH, Jia W, Huang K, Phillips NB, Hu SQ, Weiss MA. Design of an active ultrastable single-chain insulin analog: synthesis, structure, and therapeutic implications. J Biol Chem. 2008 May 23;283(21):14703-16. Epub 2008 Mar 10. PMID:18332129 doi:10.1074/jbc.M800313200
- Wan ZL, Huang K, Hu SQ, Whittaker J, Weiss MA. The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition. J Biol Chem. 2008 Jul 25;283(30):21198-210. Epub 2008 May 20. PMID:18492668 doi:10.1074/jbc.M800235200
