2hz0
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:2hz0.png|left|200px]] | [[Image:2hz0.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_2hz0", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_2hz0| PDB=2hz0 | SCENE= }} | {{STRUCTURE_2hz0| PDB=2hz0 | SCENE= }} | ||
===Abl kinase domain in complex with NVP-AEG082=== | ===Abl kinase domain in complex with NVP-AEG082=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_17164530}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 17164530 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_17164530}} | {{ABSTRACT_PUBMED_17164530}} | ||
| - | |||
| - | ==Disease== | ||
| - | Known disease associated with this structure: Leukemia, Philadelphia chromosome-positive, resistant to imatinib OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=189980 189980]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2hz0]] is a 2 chain structure of [[Proto-oncogene tyrosine-protein kinase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HZ0 OCA]. | |
| + | |||
| + | ==See Also== | ||
| + | *[[Proto-oncogene tyrosine-protein kinase|Proto-oncogene tyrosine-protein kinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:017164530</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
| Line 34: | Line 22: | ||
[[Category: Liebetanz, J.]] | [[Category: Liebetanz, J.]] | ||
[[Category: Manley, P.]] | [[Category: Manley, P.]] | ||
| + | [[Category: Transferase]] | ||
[[Category: Tyrosine kinase]] | [[Category: Tyrosine kinase]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:08:53 2009'' | ||
Revision as of 06:26, 26 July 2012
Contents |
Abl kinase domain in complex with NVP-AEG082
Template:ABSTRACT PUBMED 17164530
About this Structure
2hz0 is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Cowan-Jacob SW, Fendrich G, Floersheimer A, Furet P, Liebetanz J, Rummel G, Rheinberger P, Centeleghe M, Fabbro D, Manley PW. Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia. Acta Crystallogr D Biol Crystallogr. 2007 Jan;63(Pt 1):80-93. Epub 2006, Dec 13. PMID:17164530 doi:http://dx.doi.org/10.1107/S0907444906047287
